Book Hotels in Southeast Illinois, IL
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Top Southeast Illinois hotels

La Quinta Inn & Suites by Wyndham Effingham
1103 Avenue Of Mid America, Effingham, IL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Oct 2 to Oct 3
$109 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"We had a beautiful room and very comfortable."
Reviewed on Sep 20, 2025

Best Western Delta Inn
1509 Hampton Dr, Located right off of I-57/70, Effingham, IL
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Sep 28 to Sep 29
$100 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Would definitely stay here again
"My daughter and I came to Effingham for a concert. I didnt even realize that the venue was right across the interstate, so placement of the hotel was perfect. There were a ton of stores and food choices around, if we'd been staying longer. The breakfast was your run of the mill continental breakfast. ..."
Reviewed on Sep 20, 2025

Country Inn & Suites by Radisson, Effingham, IL
1200 N Raney, Effingham, IL
Fully refundable
$95 nightly
The price is $105 total per night from Oct 2 to Oct 3
$105 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Great staff"
Reviewed on Sep 14, 2025

Comfort Suites Mattoon East
1408 Broadway Ave E, Mattoon, IL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $95 total per night from Oct 2 to Oct 3
$95 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
"Everything was Wonderful!!!!"
Reviewed on Sep 21, 2025

Unique Suites Hotel
920 W Lincoln Ave, Charleston, IL
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $125 total per night from Oct 27 to Oct 28
$125 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, and conference ...
"Nice place"
Reviewed on Sep 21, 2025

Holiday Inn Express Metropolis by IHG
2179 East 5th Street, Metropolis, IL
Fully refundable
$94 nightly
The price is $104 total per night from Oct 26 to Oct 27
$104 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Exactly what I expected"
Reviewed on Sep 22, 2025

Economy Inn & Suites
411 E Poplar St, Harrisburg, IL
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from Oct 5 to Oct 6
$84 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features free WiFi in public areas, concierge services, and free self parking. Enjoy the free continental breakfast each morning. A terrace and a ...
"The staff were kind n friendly rooms were nice n clean good atmosphere i would definatly visit yhere agian"
Reviewed on Sep 15, 2025

Quality Inn & Suites Metropolis I-24
2118 E 5th St, Metropolis, IL
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $68 total per night from Oct 12 to Oct 13
$68 total
Oct 12 - Oct 13
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
"Nice clean room."
Reviewed on Sep 23, 2025

Days Inn & Suites by Wyndham Casey
933 N Route 49, Casey, IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Sep 28 to Sep 29
$72 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
"Had a great time visiting Casey for the first time. Motel was convenient for all the attractions."
Reviewed on Sep 22, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Illinois hotels

Days Inn by Wyndham Charleston
810 West Lincoln Avenue, Charleston, IL
$82 nightly
The price is $91 total per night from Sep 28 to Sep 29
$91 total
Sep 28 - Sep 29
Total with taxes and fees
7.6/10 Good! (755 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Southeast Illinois hotel reviews by fellow wanderers

Quality Inn & Suites Metropolis I-24
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Nice clean room. "
A verified traveler stayed at Quality Inn & Suites Metropolis I-24
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An Attraction
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